Input the following command: BASEsurv1.0.exe CelCycle1.txt 6178 5 ChRatioYPD203.txt 6229 203 1000 CCres1.xls Note: [1]BASEsurv1.0.exe -- the program name [2]CelCycle1.txt -- the expression data file (in log ratio scale), the first row is the experiment name; the first column is gene names [3]6178 -- the name of genes in the expression data [4]5 -- the number of profiles in the expression data [5]ChRatioYPD203.txt -- ChIP-chip data (contains the binding scores of 203 TF for 6229 genes [6]6229 -- the number of genes in ChIP-chip data [7]203 -- the number of TFs in ChIP-chip data; binding in YPD medium condition [8]1000 -- permutation times [9]CCres1.xls -- the output files Run the program: Click the file "run.bat"; you can change the bat file by yourself