Research Interests Publications Non Technical Research Description Contact Info


I've moved to the Church lab. My new page is here.
New Contact info: tagianoulis at gmail dot com

About Me

I recently completed my PhD in Computational Biology and Bioinformatics at Yale University as a joint student with Mark Gerstein and Michael Snyder. As a PhD student, I worked on problems in four major areas: Microbial Genome Sequencing (specifically the use of short read technology for de novo sequencing and assembly), Gene Regulatory Network Evolution, Metagenomics, and Multidimensional Data Integration.

I am now finishing up a short post doc with Scott Strobel and Mark Gerstein where I am investigating computational approaches to study fuel producing micro-organisms. I leave in the fall to work with George Church at Harvard Medical School.

I am passionate about triathlon, cycling, off road bike-touring, fixing aforementioned bikes, teaching English as a Second Language, and high throughput sequencing.

In the Gerstein lab, I am part of the networks subgroup. Our goal is to use graph theoretical approaches to solve interesting biological problems.

Research Interests (more details coming soon)

Microbial Genome Sequencing
Gene Regulatory Network Evolution


*Gianoulis TA, *Raes J, Patel PV, Bjornson R, Korbel JO, Letunic I, Yamada T Paccanaro A, Jensen LJ, Snyder M, Bork P, Gerstein MB.
Quantifying environmental adaptation of metabolic pathways in metagenomics.
Proc Natl Acad Sci 2009, 106: 1374-9. (highlighted in Science and Nature Genetics).

Borneman AR, Gianoulis TA, Zhang ZD, Yu H, Rozowsky J, Seringhaus MR, Wang LY, Gerstein M, Snyder M.
Divergence of transcription factor binding sites across related yeast species.
Science. 2007 Aug 10;317(5839):815-9.

Lu LJ, Sboner A, Huang YJ, Lu HX, Gianoulis TA, Yip KY, Kim PM, Montelione GT, Gerstein MB.
Comparing classical pathways and modern networks: towards the development of an edge ontology.
Trends Biochem Sci. 2007 Jul;32(7):320-31. Epub 2007 Jun 20.

Smith MG, Gianoulis TA, Pukatzki S, Mekalanos JJ, Ornston LN, Gerstein M, Snyder M.
New insights into Acinetobacter baumannii pathogenesis revealed by high-density pyrosequencing and transposon mutagenesis.
Genes Dev. 2007 Mar 1;21(5):601-14. (featured on NOVA Science Now)

Goh CS*, Gianoulis TA*, Liu Y, Li J, Paccanaro A, Lussier YA, Gerstein M
. Integration of curated databases to identify genotype-phenotype associations. BMC Genomics. 2006 Oct 12;7:257.

*These authors contributed equally to this work.

Non-Technical Research Description (aka What does Tara do?)

After several years in grad school (translation many Christmases with bewildered family members), I tried to write a non-technical description of my work. I've provided a link to this somewhat whimsical three-part series below.

What does Tara do? A three part series
Part I What is Computational Biology?
Part II What is Machine Learning?
Part III But what do you do?

Contact Info

Computational Biology and Bioinformatics
Yale University
266 Whitney Avenue, Bass 437
P.O. Box 208114
New Haven, CT 06520
Phone: (203) 432-5405
tara dot gianoulis at yale dot edu