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Xinmeng Jasmine Mu, Ph.D.
Email: xmu@broadinstitute.org Address: 301 Binney St., 5th floor Cambridge MA 02142 |
| Education |
| 2007 - 2012 | |
Advisor: Prof. Mark Gerstein |
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| 2007 - 2009 | |
Co-advisors: Prof. Mark Gerstein & Prof. Michael Snyder |
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| 2003 - 2007 | B.S., in Biological Science, Peking University |
| Research Experience | |
| 2013-now | Computational Biologist, Cancer Program, The Broad Institute of Harvard & MIT |
| Studying genomic alterations in cancer to elucidate tumor origin, heterogeneity, and drug resistence mechanisms | |
| 2007 - 2012 | Graduate Research Assistant, Yale University |
Developed computational tools for characterizing genomic variants and integrative frameworks for studying selection pressure on functional elements |
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| 2008 | Rotation Student, Yale University |
Developed computational frameworks to identify transposable elements from next-generation sequencing data |
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| 2008 | Rotation Student, Yale University |
Investigated the cooperative inhibition of virus production by distinctive cytokine families and their relation to promoter elements |
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| 2008 | Rotation Student, Yale University |
Investigated the regulation of the immune system by Bcl-rambo gene in mice |
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| 2006 - 2007 | Undergrad Research Assistant, National Institute of Biological Sciences, Beijing |
Studied the impact of plant light signaling on histone modifications |
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| 2006 | Summer Intern, Harvard Stem Cell Institute |
Studied the molecular regulation of poised genes in multipotential hematopoietic cells |
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| 2005 - 2006 | Undergraduate Research Assistant, Peking University |
Hong-Bing Shu Group |
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Carried out a yeast-two-hybrid screen for human C20-interacting proteins |
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| 2005 | Summer Student, Yale University |
Studied the Arabidopsis light signaling pathway |
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| International conferences | |
| 2012 | Attendee, 1000 Genomes Project Meeting, Cold Spring Harbor, NY |
| 2012 | Invited talk, XGen Congress and Expo Conference, San Diego, CA |
| Topic: Analysis of genomic variants in non-coding elements using population-scale sequencing data from the 1000 Genomes Project | |
| 2012 | Moderator, Java and Jive Discussion Group, XGen Congress and Expo Conference, San Diego, CA |
| Topic: Personal genomics and privacy | |
| 2011 | Attendee, The Biology of Genomes, Cold Spring Harbor, NY |
| 2011 | Attendee, 1000 Genomes Project Meeting, Cold Spring Harbor, NY |
| 2010 | Poster presentation, Annual Centers of Excellence in Genomic Science (CEGS) Meeting, Phoenix, AZ |
| Topic: Nucleotide-resolution analysis of structural variants using BreakSeq and a breakpoint library | |
| 2010 | Poster presentation, The Biology of Genomes Conference - Cold Spring Harbor, NY Spring |
| Topic: Nucleotide-resolution analysis of structural variants using BreakSeq and a breakpoint library | |
| 2010 | Attendee, 1000 Genomes Project Meetings, Cold Spring Harbor, NY & Washington D.C. |
| 2009 | Attendee, 1000 Genomes Project Meeting, Cold Spring Harbor, NY |
| 2007 | Volunteer staff, International Conference on Arabidopsis Research, Beijing, China. |
Facilitated with organizing the conference logistics, including registration, plenary sessions, and poster sessions |
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| Teaching | |
| 2012 | Teaching Fellow, Molecular Biology (MCDB200) |
| Department of Molecular, Cellular & Developmental biology, Yale University | |
| Instructors: Prof. Anna Pyle, Prof. Stephen Dellaporta, Prof. Farren Isaacs | |
| Leading weekly discussion sessions on scientific literature reading, grading exams and homework assignments. | |
| 2010 | Teaching Fellow, Molecular Biology (MCDB200) |
| Department of Molecular, Cellular & Developmental biology, Yale University | |
| Instructors: Prof. Stephen Dellaporta, Prof. Sidney Altman, Prof. Thomas Pollard, and Prof. Matthew Rodeheffer | |
| Leading weekly discussion sessions on scientific literature reading, grading exams and homework assignments. | |
Skills Programming languages & assoc.: Perl, R, Python, C/C++, Shell, and SQL. Operation systems: Unix/Linux, Mac, Windows. Mathematical and statistical: Experienced in basic bioinformatics techniques, data mining, machine learning, probability, parameter estimation, linear models, multivariate statistics, data structure and algorithm design, etc. Computational genomics: Experienced in next-generation sequencing data processing and analysis, genomic variants and evolutionary pressure characterization, networks analysis, and functional elements and pseudogene characterization. Experimental: Basic techniques for molecular biology, cell biology, biochemistry and immunology.
Interests My interests include cancer research, genomics, biotechnology, classical music, seafood, and travelling. |
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