PO Box 208114 • Yale University

New Haven, CT 06520 • 203-432-5405

chernsing.goh@yale.edu

http://homes.gersteinlab.org/people/goh/

 

Current Position:

Yale University, 2002 – present

NIH Postdoctoral Fellow, Molecular Biophysics and Biochemistry

Advisor – Professor Mark Gerstein

 

Education:

University of California, San Francisco, 1998-2002

PhD, Biological and Medical Informatics

Thesis – “Characterizing the Co-Evolution of Protein-Protein Interactions”

Graduate Advisor - Professor Fred Cohen

 

University of Wisconsin-Madison, 1990-1994 

Bachelor of Science, Molecular Biology

Graduated with Honors

 

Honors and Awards:

2003-present	NIH Ruth L Kirschstein National Research Postdoctoral Fellow
2001-2002	Burroughs Wellcome - UCSF Interfaces in Science Award
1990-1994	Dean's List
1990-1994	University of Wisconsin, Madison Full Tuition Scholarship

 

Professional Experience:

1997-1998	Research Associate - Department of Molecular and Cell Biology
	Principle Investigator: Professor David Raulet
	University of California, Berkeley
1996-1997	Research Specialist - Department of Neurological Surgery
	Principle Investigator: Dr. Behnam Badie
	University of Wisconsin, Madison
1995-1996	Research Assistant - Department of Human Oncology
	Principle Investigator: Professor Michael Gould
	University of Wisconsin, Madison
1994-1996	Research Specialist - Department of Psychiatry
	Principle Investigator: Professor Lorey Takahashi
	University of Wisconsin, Madison

Research and Publications:

Goh CS, Gianoulis TA, Liu Y, Li J, Paccanaro A, Lussier YA, Gerstein M (2006). Integration of curated databases to identify genotype-phenotype associations. BMC Genomics. 7:257.

 

Liu Y, Li J, Sam L, Goh CS, Gerstein M, Lussier YA (2006). An integrative genomic approach to uncover molecular mechanisms of prokaryotic traits. PLoS Comput Biol.2(11)e159.

 

Lehnert U, Xia Y, Royce TE, Goh CS, Liu Y, Senes A, Yu H, Zhang ZL, Engelman DM, Gerstein M (2004). Computational analysis of membrane proteins: genomic occurrence, structure prediction and helix interactions.Q Rev Biophys. 37(2):121-46.

 

Goh CS, Milburn D, Gerstein M (2004). “Conformational Changes Associated with Protein-Protein Interactions,” Curr Opin Struct Biol 14(1):104-9.

 

Goh CS, Lan N, Douglas SM, Wu B, Echols N, Smith A, Milburn D, Montelione GT, Zhao H, Gerstein M (2004). “Mining the Structural Genomics Pipeline: Identification and Analysis of Protein Properties that Affect High-Throughput Experimental Analysis,” J Molecular Biology 336(1):115-30.

 

Goh CS, Lan N, Echols N, Douglas SM, Milburn D, Bertone P, Xiao R, Ma LC, Zheng D, Wunderlich Z, Acton T, Montelione GT, Gerstein M (2003). “SPINE 2: A System for Collaborative Structural Proteomics within a Federated Database Framework.” Nucleic Acids Research 31(11): 2833-2838.

 

Devoto A, Hartmann HA, Piffanelli P, Elliott C, Simmons C, Taramino G, Goh CS, Cohen FE, Emerson BC, Schulze-Lefert P, Panstruga R (2003).  “Molecular Phylogeny and Evolution of the Plant-Specific Seven Transmembrane MLO Family.” J Molecular Evolution 56(1):  77-88.

 

Goh CS, Cohen FE (2002). "Co-Evolutionary Analysis Reveals Insights into Protein-Protein Interactions," J Molecular Biology  324(1): 177-92.

 

Beisser PS, Goh CS, Cohen FE, Michelson S (2002).  “Viral Chemokine Receptors and Chemokines in Human Cytomegalovirus Trafficking and Interaction with the Immune System.” Curr Top Microbiol Immunol 269:  203-234.

 

Goh CS, Bogan AA, Joachimiak J, Walther D, Cohen FE (2000).  “Co-evolution of proteins with their interaction partners.” J Molecular Biology 299(2):  283-293. 

 

Badie B, Goh CS, Klaver J, Herweijer H, Boothman D (1999).  “Collective radiation and p53 gene therapy of malignant glioma cells.” Cancer Gene Ther 6(2):  155-162.

 

Chauvet AE, Kesava PP, Goh CS, Badie B (1998).  “Selective intra-arterial gene delivery into a canine meningioma.” J Neurosurgery 88(5):  870-873.

 

Takahashi LK, Goh CS (1998).  “Glucocorticoid facilitation of cholinergic development in the rat hippocampus.”  Neuroscience 83(4): 1145-1153.

 

Takahashi LK, Goh CS (1997).  “Presynaptic muscarinic cholinergic receptors in the dorsal hippocampus regulate behavioral inhibition of preweanling rats.” Brain Research 731(1-2):  230-235.

 

Technical Skills:

Programming:	Perl, Java, C, Python, SQL, JavaScript, HTML, CGI programming
Operating Systems:	Unix, Linux, SGI, Windows 98/NT/2000/XP, Mac OS
Software:	S-Plus, R, BLAST, FASTA, ClustalW, Phylip, GCG, Modeller, DALI, GRASP, Delphi, MEME, HMMER, PyMol

Also available in PDF format.